Staphylococcus Aureus and Methicillin-Resistant Staphylococcus Aureus Nucleic Acid Detection Kit

Staphylococcus aureus is one of the important pathogenic bacteria of nosocomial infection. Staphylococcus aureus (SA) belongs to the staphylococcus and is a representative of Gram-positive bacteria, which can produce a variety of toxins and invasive enzymes. The bacteria have the characteristics of wide distribution, strong pathogenicity and high resistance rate. Thermostable nuclease gene (nuc) is a highly conserved gene of staphylococcus aureus.

In recent years, due to the extensive use of hormones and immune preparations and the abuse of broad-spectrum antibiotics, nosocomial infections caused by Methicillin-resistant Staphylococcus aureus (MRSA) in Staphylococcus have been on the rise. The national average detection rate of MRSA was 30.2% in 2019 in China. MRSA is divided into healthcare-associated MRSA (HA-MRSA), community-associated MRSA (CA-MRSA), and livestock-associated MRSA (LA-MRSA). CA-MRSA, HA-MRSA, LA-MRSA have great differences in microbiology, bacterial resistance (eg, HA-MRSA shows more multidrug resistance than CA-MRSA) and clinical characteristics (eg infection site). According to these characteristics, CA-MRSA and HA-MRSA can be distinguished. However, the differences between CA-MRSA and HA-MRSA are narrowing due to the constant movement of people between hospitals and communities. MRSA is multi-drug resistant, not only resistant to β-lactam antibiotics, but also to aminoglycosides, macrolides, tetracyclines and quinolones to varying degrees. There are large regional differences in drug resistance rates and different trends. MRSA can invade the body through skin wounds, hair follicles, blood and other causes suppurative infection, and patients with skin diseases and burns are extremely susceptible to MRSA infection. Pneumonia is one of the most common clinical infections of MRSA, and inappropriate treatment is an important cause of high mortality.