Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR) – Macro & Micro-Test

Product name

Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR)
Orthopox Virus Universal Type/Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR)

Certificate

CE

Epidemiology

Monkeypox (MP) is an acute zoonotic infectious disease caused by Monkeypox Virus (MPV). The disease is mainly transmitted by animals, and humans could become infected by being bitten by infected animals or by direct contact with the blood, body fluids and rash of infected animals. The virus can also be transmitted between people, primarily through respiratory droplets during prolonged, direct face-to-face contact or through direct contact with a patient’s body fluids or contaminated objects^[1-2].

The clinical symptoms of monkeypox infection in humans are similar to those of smallpox, generally after a 12-day incubation period, appearing fever, headache, muscle and back pain, enlarged lymph nodes, fatigue and discomfort. The rash appears after 1-3 days of the fever, usually first on the face, but also in other parts. The disease course generally lasts 2-4 weeks, and the mortality rate is 1%-10%. Lymphadenopathy is one of the main differences between this disease and smallpox^[3].

Features

● Multiplex PCR Amplification Technology
● Accuracy: Internal control, fully monitor the experimental process to ensure the quality of Experiments.
● Rapid: Rapid PCR amplification shorts detection time, resulted in 40 minutes
● High sensitivity: 200 Copies/mL
● Triple PCR assay: Dual target gene(MPV-1 & MPV-2) of Monkeypox virus + human endogenous gene

Channel

PCR Amplification Conditions Setting

Technical Parameters

Main Components

Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR)

Orthopox Virus Universal Type/Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR)

Total PCR Solution

Option 1.

Option 2.

References

[1] Centers for Disease Control and Prevention. Human monkeypox-Kasai Oriental, Zaire, 1996-1997.MMWR. 1997, 46:304-307.
[2] Beer EM, Rao VB. A systematic review of the epidemiology of human monkeypox outbreaks and implications for outbreak strategy. PLoS Negl Trop Dis 2019 10;13(10).
[3] Jezek Z, Marennikova SS, Mutumbo M, et al. Human monkeypox: a study of 2,510 contacts of 214 patients. J Infect Dis 1986 Oct;154(4).